Drug interactions
Formoterol-mometasone + Sorafenib
Severity: Moderate
Formoterol-mometasone and Sorafenib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sorafenib can prolong the QT interval, and formoterol may add to this effect and lower potassium. The combination may increase arrhythmia risk in predisposed patients.
What this interaction means in plain words
Formoterol-mometasone and Sorafenib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Sorafenib belongs to Oncology.
Why it happens
Additive QTc prolongation, with possible beta-2-agonist-induced hypokalemia.
What to do
Monitor ECG and electrolytes, especially in patients with cardiac disease or electrolyte disturbances. Correct hypokalemia and hypomagnesemia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Sorafenib
Frequently asked questions
Can I take Formoterol-mometasone with Sorafenib?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Sorafenib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sorafenib can prolong the QT interval, and formoterol may add to this effect and lower potassium. The combination may increase arrhythmia risk in predisposed patients.
How serious is the interaction between Formoterol-mometasone and Sorafenib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes, especially in patients with cardiac disease or electrolyte disturbances. Correct hypokalemia and hypomagnesemia.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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