Drug interactions
Forskolin + Hydrochlorothiazide-lisinopril
Severity: Minor
Forskolin and Hydrochlorothiazide-lisinopril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin activates adenylate cyclase and has vasodilating properties, so it could add to the blood pressure lowering of hydrochlorothiazide-lisinopril. Clinical data are limited and the effect is likely small.
What this interaction means in plain words
Forskolin and Hydrochlorothiazide-lisinopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive vasodilation; the mechanism is not well established in humans.
What to do
Monitor blood pressure if forskolin supplements are started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-lisinopril
- Dofetilide + Hydrochlorothiazide-lisinopril Contraindicated
- Hydrochlorothiazide-lisinopril + Sacubitril / valsartan Contraindicated
- Amifostine + Hydrochlorothiazide-lisinopril Major
- Amiloride + Hydrochlorothiazide-lisinopril Major
- Benazepril + Hydrochlorothiazide-lisinopril Major
- Bendroflumethiazide + Hydrochlorothiazide-lisinopril Major
Frequently asked questions
Can I take Forskolin with Hydrochlorothiazide-lisinopril?
MediHelp rates the interaction as minor. Forskolin and Hydrochlorothiazide-lisinopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Forskolin activates adenylate cyclase and has vasodilating properties, so it could add to the blood pressure lowering of hydrochlorothiazide-lisinopril. Clinical data are limited and the effect is likely small.
How serious is the interaction between Forskolin and Hydrochlorothiazide-lisinopril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if forskolin supplements are started or stopped.
What other medicines interact with Hydrochlorothiazide-lisinopril?
MediHelp also lists interactions of Hydrochlorothiazide-lisinopril with, for example, Dofetilide, Sacubitril / valsartan, Amifostine. The full list is on the Hydrochlorothiazide-lisinopril page.
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