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Drug interactions

Foscarnet + Quetiapine

Severity: Major

Foscarnet and Quetiapine: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Quetiapine can prolong the QT interval, particularly in overdose or with other risk factors, and foscarnet adds QT effects and electrolyte loss. The combination may increase the risk of arrhythmia.

What this interaction means in plain words

Foscarnet and Quetiapine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Foscarnet belongs to Anti Virals; Quetiapine belongs to Central Nervous System.

Evidence level: Moderate

Why it happens

Additive QT prolongation with foscarnet-induced electrolyte disturbance.

What to do

Monitor ECG and electrolytes and correct deficits. Consider an alternative antipsychotic with lower QT liability if QTc increases.

What to ask your pharmacist

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Foscarnet with Quetiapine?

MediHelp rates the interaction as major. Foscarnet and Quetiapine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Quetiapine can prolong the QT interval, particularly in overdose or with other risk factors, and foscarnet adds QT effects and electrolyte loss. The combination may increase the risk of arrhythmia.

How serious is the interaction between Foscarnet and Quetiapine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes and correct deficits. Consider an alternative antipsychotic with lower QT liability if QTc increases.

What other medicines interact with Foscarnet?

MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.

Full monographs, dosing and an interaction checker in the MediHelp app

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