Drug interactions
Furosemide + Indacaterol inhaled
Severity: Moderate
Furosemide and Indacaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indacaterol, a long-acting beta-2 agonist, can lower serum potassium, and furosemide causes potassium loss. Together hypokalemia may be more pronounced, which can promote arrhythmias, especially with hypoxia or other QT-prolonging drugs.
What this interaction means in plain words
Furosemide and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from renal potassium wasting (furosemide) and beta-2 mediated intracellular potassium shift (indacaterol).
What to do
Monitor serum potassium periodically, particularly at initiation or in patients with cardiac disease or hypoxia, and correct deficits.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Furosemide with Indacaterol inhaled?
MediHelp rates the interaction as moderate. Furosemide and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indacaterol, a long-acting beta-2 agonist, can lower serum potassium, and furosemide causes potassium loss. Together hypokalemia may be more pronounced, which can promote arrhythmias, especially with hypoxia or other QT-prolonging drugs.
How serious is the interaction between Furosemide and Indacaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium periodically, particularly at initiation or in patients with cardiac disease or hypoxia, and correct deficits.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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