Drug interactions
Furosemide + Neomycin po
Severity: Moderate
Furosemide and Neomycin po: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Loop diuretics and aminoglycosides both injure the cochlea and kidney. Oral neomycin is poorly absorbed, but absorption can increase with damaged gut mucosa or renal impairment, so the risk of hearing loss and kidney injury is raised in those settings.
What this interaction means in plain words
Furosemide and Neomycin po can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive ototoxicity and nephrotoxicity, with loop diuretic volume depletion further raising aminoglycoside exposure and renal vulnerability.
What to do
Avoid the combination in patients with renal impairment, inflammatory bowel disease or prolonged therapy; otherwise monitor renal function and hearing and keep the patient well hydrated.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Furosemide with Neomycin po?
MediHelp rates the interaction as moderate. Furosemide and Neomycin po can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Loop diuretics and aminoglycosides both injure the cochlea and kidney. Oral neomycin is poorly absorbed, but absorption can increase with damaged gut mucosa or renal impairment, so the risk of hearing loss and kidney injury is raised in those settings.
How serious is the interaction between Furosemide and Neomycin po?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in patients with renal impairment, inflammatory bowel disease or prolonged therapy; otherwise monitor renal function and hearing and keep the patient well hydrated.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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