Drug interactions
Furosemide + Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol
Severity: Moderate
Furosemide and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bowel preparation causes fluid and electrolyte shifts, and furosemide adds to volume depletion and urinary potassium loss. Together they raise the risk of dehydration, hypokalemia, hypomagnesemia and renal injury.
What this interaction means in plain words
Furosemide and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive fluid and electrolyte depletion from diuresis and osmotic bowel cleansing.
What to do
Ensure adequate hydration and consider holding furosemide on the day of bowel preparation if clinically feasible. Check electrolytes and renal function in high-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Furosemide with Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol?
MediHelp rates the interaction as moderate. Furosemide and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bowel preparation causes fluid and electrolyte shifts, and furosemide adds to volume depletion and urinary potassium loss. Together they raise the risk of dehydration, hypokalemia, hypomagnesemia and renal injury.
How serious is the interaction between Furosemide and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure adequate hydration and consider holding furosemide on the day of bowel preparation if clinically feasible. Check electrolytes and renal function in high-risk patients.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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