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Drug interactions

Furosemide + Sulfasalazine

Severity: Minor

Furosemide and Sulfasalazine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

There is no established clinically important interaction between these drugs; sulfasalazine does not raise potassium in a way that offsets furosemide. Loop diuretic potassium loss should simply be monitored as usual.

What this interaction means in plain words

Furosemide and Sulfasalazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

No established mechanism for a clinically significant interaction.

What to do

No specific action beyond routine monitoring of serum potassium during furosemide therapy.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Furosemide with Sulfasalazine?

MediHelp rates the interaction as minor. Furosemide and Sulfasalazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. There is no established clinically important interaction between these drugs; sulfasalazine does not raise potassium in a way that offsets furosemide. Loop diuretic potassium loss should simply be monitored as usual.

How serious is the interaction between Furosemide and Sulfasalazine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action beyond routine monitoring of serum potassium during furosemide therapy.

What other medicines interact with Furosemide?

MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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