Drug interactions
Furosemide + Telmisartan-amlodipine
Severity: Moderate
Furosemide and Telmisartan-amlodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Furosemide adds to the blood pressure lowering of telmisartan-amlodipine and can cause volume depletion, hypotension and acute kidney injury. Potassium changes may be opposing, since furosemide lowers and telmisartan raises it.
What this interaction means in plain words
Furosemide and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Furosemide belongs to Cardiovascular; Telmisartan-amlodipine belongs to Cardiovascular.
Why it happens
Loop diuretic natriuresis activates the renin-angiotensin system, and ARB blockade increases dependence on volume status, adding hypotensive and renal risk.
What to do
Monitor blood pressure, renal function and electrolytes after starting or changing doses. Reduce the diuretic dose if volume depletion develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Furosemide and Telmisartan-amlodipine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Furosemide with Telmisartan-amlodipine?
MediHelp rates the interaction as moderate. Furosemide and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Furosemide adds to the blood pressure lowering of telmisartan-amlodipine and can cause volume depletion, hypotension and acute kidney injury. Potassium changes may be opposing, since furosemide lowers and telmisartan raises it.
How serious is the interaction between Furosemide and Telmisartan-amlodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, renal function and electrolytes after starting or changing doses. Reduce the diuretic dose if volume depletion develops.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
