Drug interactions
Furosemide + Terbutaline
Severity: Moderate
Furosemide and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower serum potassium, so combined use can cause clinically significant hypokalemia and raise the risk of arrhythmia. The risk is highest with high-dose or parenteral terbutaline.
What this interaction means in plain words
Furosemide and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Furosemide belongs to Cardiovascular; Terbutaline belongs to Respiratory.
Why it happens
Additive hypokalemia from beta-2 mediated intracellular potassium shift and loop diuretic renal potassium loss.
What to do
Monitor serum potassium and replace it as needed, especially in patients with cardiac disease or on digoxin.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Furosemide with Terbutaline?
MediHelp rates the interaction as moderate. Furosemide and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower serum potassium, so combined use can cause clinically significant hypokalemia and raise the risk of arrhythmia. The risk is highest with high-dose or parenteral terbutaline.
How serious is the interaction between Furosemide and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and replace it as needed, especially in patients with cardiac disease or on digoxin.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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