Drug interactions
Furosemide + Thiamine
Severity: Minor
Furosemide and Thiamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chronic loop diuretic use increases urinary loss of thiamine and may contribute to thiamine deficiency, especially in patients with heart failure or poor nutrition. Deficiency may worsen cardiac function.
What this interaction means in plain words
Furosemide and Thiamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Increased urinary flow from loop diuresis enhances renal excretion of water-soluble thiamine.
What to do
Consider thiamine supplementation in patients on long-term high-dose furosemide who have poor intake or heart failure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Furosemide with Thiamine?
MediHelp rates the interaction as minor. Furosemide and Thiamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chronic loop diuretic use increases urinary loss of thiamine and may contribute to thiamine deficiency, especially in patients with heart failure or poor nutrition. Deficiency may worsen cardiac function.
How serious is the interaction between Furosemide and Thiamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider thiamine supplementation in patients on long-term high-dose furosemide who have poor intake or heart failure.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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