Drug interactions
Ganaxolone + Thioridazine
Severity: Moderate
Ganaxolone and Thioridazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ganaxolone is a neuroactive steroid that causes somnolence, and thioridazine is also sedating. Concurrent use may increase drowsiness and impaired alertness.
What this interaction means in plain words
Ganaxolone and Thioridazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ganaxolone belongs to Central Nervous System; Thioridazine belongs to Central Nervous System.
Why it happens
Additive CNS depression.
What to do
Monitor for excessive sedation and consider reducing doses if drowsiness is troublesome. Counsel patients on avoiding hazardous activities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Thioridazine
- Abiraterone + Thioridazine Contraindicated
- Adagrasib + Thioridazine Contraindicated
- Amiodarone + Thioridazine Contraindicated
- Amisulpride + Thioridazine Contraindicated
- Amitriptyline + Thioridazine Contraindicated
- Amoxapine + Thioridazine Contraindicated
Other interactions of Ganaxolone
Frequently asked questions
Can I take Ganaxolone with Thioridazine?
MediHelp rates the interaction as moderate. Ganaxolone and Thioridazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ganaxolone is a neuroactive steroid that causes somnolence, and thioridazine is also sedating. Concurrent use may increase drowsiness and impaired alertness.
How serious is the interaction between Ganaxolone and Thioridazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation and consider reducing doses if drowsiness is troublesome. Counsel patients on avoiding hazardous activities.
What other medicines interact with Thioridazine?
MediHelp also lists interactions of Thioridazine with, for example, Abiraterone, Adagrasib, Amiodarone. The full list is on the Thioridazine page.
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