Drug interactions
Garlic + Ketoprofen
Severity: Minor
Garlic and Ketoprofen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Garlic supplements have mild antiplatelet activity that may add to the antiplatelet effect and GI bleeding risk of NSAIDs. Evidence is limited to theoretical considerations and a few case reports.
What this interaction means in plain words
Garlic and Ketoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Garlic belongs to Gastrointestinal Tract; Ketoprofen belongs to Musculoskeletal.
Why it happens
Additive inhibition of platelet aggregation; garlic constituents may inhibit platelet function.
What to do
Monitor for bruising or bleeding in patients taking concentrated garlic supplements with ketoprofen, and consider stopping garlic supplements before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Other interactions of Garlic
- Garlic + Saquinavir Major
- Aceclofenac + Garlic Moderate
- Acemetacin + Garlic Moderate
- Aescin + Garlic Moderate
- Alteplase + Garlic Moderate
- Argatroban + Garlic Moderate
Frequently asked questions
Can I take Garlic with Ketoprofen?
MediHelp rates the interaction as minor. Garlic and Ketoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Garlic supplements have mild antiplatelet activity that may add to the antiplatelet effect and GI bleeding risk of NSAIDs. Evidence is limited to theoretical considerations and a few case reports.
How serious is the interaction between Garlic and Ketoprofen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bruising or bleeding in patients taking concentrated garlic supplements with ketoprofen, and consider stopping garlic supplements before surgery.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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