Drug interactions
Gemcitabine + Influenza virus vaccine adjuvanted
Severity: Moderate
Gemcitabine and Influenza virus vaccine adjuvanted: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gemcitabine may diminish the immune response to the adjuvanted H5N1 influenza vaccine, reducing protection.
What this interaction means in plain words
Gemcitabine and Influenza virus vaccine adjuvanted can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Cytotoxic immunosuppression blunts the immune response to vaccine antigens.
What to do
Time vaccination before chemotherapy or during periods of immune recovery. Consider additional protective measures in high-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Gemcitabine
Frequently asked questions
Can I take Gemcitabine with Influenza virus vaccine adjuvanted?
MediHelp rates the interaction as moderate. Gemcitabine and Influenza virus vaccine adjuvanted can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gemcitabine may diminish the immune response to the adjuvanted H5N1 influenza vaccine, reducing protection.
How serious is the interaction between Gemcitabine and Influenza virus vaccine adjuvanted?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Time vaccination before chemotherapy or during periods of immune recovery. Consider additional protective measures in high-risk patients.
What other medicines interact with Gemcitabine?
MediHelp also lists interactions of Gemcitabine with, for example, Adenovirus types 4 and 7 live, Axicabtagene ciloleucel, Belatacept. The full list is on the Gemcitabine page.
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