Drug interactions
Gemifloxacin + Olodaterol inhaled
Severity: Moderate
Gemifloxacin and Olodaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gemifloxacin prolongs the QT interval and beta2 agonists can cause hypokalemia and cardiac stimulation. Together they may potentiate the risk of ventricular arrhythmias in susceptible patients.
What this interaction means in plain words
Gemifloxacin and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation with beta2-agonist-induced hypokalemia and sympathetic effects.
What to do
Monitor for palpitations or syncope and check potassium in patients with cardiac risk factors. Consider an alternative antibiotic in those with prior arrhythmia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Gemifloxacin
- Arsenic trioxide + Gemifloxacin Contraindicated
- Dofetilide + Gemifloxacin Contraindicated
- Gemifloxacin + Ibutilide Contraindicated
- Gemifloxacin + Pimozide Contraindicated
- Gemifloxacin + Thioridazine Contraindicated
- Gemifloxacin + Vandetanib Contraindicated
Frequently asked questions
Can I take Gemifloxacin with Olodaterol inhaled?
MediHelp rates the interaction as moderate. Gemifloxacin and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gemifloxacin prolongs the QT interval and beta2 agonists can cause hypokalemia and cardiac stimulation. Together they may potentiate the risk of ventricular arrhythmias in susceptible patients.
How serious is the interaction between Gemifloxacin and Olodaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for palpitations or syncope and check potassium in patients with cardiac risk factors. Consider an alternative antibiotic in those with prior arrhythmia.
What other medicines interact with Gemifloxacin?
MediHelp also lists interactions of Gemifloxacin with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Gemifloxacin page.
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