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Drug interactions

Gentamicin + Levosalbutamol

Severity: Moderate

Gentamicin and Levosalbutamol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Gentamicin can cause renal potassium and magnesium wasting, and beta-2 agonists lower potassium by shifting it into cells. Together they may contribute to hypokalemia, with a risk of arrhythmia.

What this interaction means in plain words

Gentamicin and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Gentamicin belongs to Anti Bacterial; Levosalbutamol belongs to Respiratory.

Evidence level: Low

Why it happens

Beta-2 mediated intracellular potassium shift combined with aminoglycoside-related renal electrolyte wasting.

What to do

Monitor potassium and magnesium during combined therapy and replace deficits. Be especially careful with high-dose or nebulized levosalbutamol.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Gentamicin with Levosalbutamol?

MediHelp rates the interaction as moderate. Gentamicin and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gentamicin can cause renal potassium and magnesium wasting, and beta-2 agonists lower potassium by shifting it into cells. Together they may contribute to hypokalemia, with a risk of arrhythmia.

How serious is the interaction between Gentamicin and Levosalbutamol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor potassium and magnesium during combined therapy and replace deficits. Be especially careful with high-dose or nebulized levosalbutamol.

What other medicines interact with Levosalbutamol?

MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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