Drug interactions
Gentamicin + Microbiota
Severity: Moderate
Gentamicin and Microbiota: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral microbiota products depend on bacterial spores engrafting in the gut. Systemic gentamicin has limited intestinal exposure, but antibacterial effects could still reduce engraftment.
What this interaction means in plain words
Gentamicin and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Antibacterial activity may reduce colonization by the administered bacteria.
What to do
Finish the antibiotic course and observe the labeled washout interval of a few days before giving the microbiota product.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Gentamicin
- Cidofovir + Gentamicin Contraindicated
- Adefovir + Gentamicin Major
- Amikacin + Gentamicin Major
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Major
- Amphotericin b deoxycholate + Gentamicin Major
- Amphotericin b + Gentamicin Major
Frequently asked questions
Can I take Gentamicin with Microbiota?
MediHelp rates the interaction as moderate. Gentamicin and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral microbiota products depend on bacterial spores engrafting in the gut. Systemic gentamicin has limited intestinal exposure, but antibacterial effects could still reduce engraftment.
How serious is the interaction between Gentamicin and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish the antibiotic course and observe the labeled washout interval of a few days before giving the microbiota product.
What other medicines interact with Gentamicin?
MediHelp also lists interactions of Gentamicin with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Gentamicin page.
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