Drug interactions
Gentamicin + Telmisartan-amlodipine
Severity: Moderate
Gentamicin and Telmisartan-amlodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gentamicin is nephrotoxic, and with an ARB such as telmisartan, which reduces glomerular filtration pressure, the risk of acute kidney injury and electrolyte disturbance may increase. Gentamicin can also cause renal potassium and magnesium wasting.
What this interaction means in plain words
Gentamicin and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Gentamicin belongs to Anti Bacterial; Telmisartan-amlodipine belongs to Cardiovascular.
Why it happens
Aminoglycoside tubular toxicity combines with ARB-reduced glomerular perfusion, increasing renal injury risk.
What to do
Monitor creatinine, potassium and magnesium and gentamicin levels during therapy. Consider temporarily holding telmisartan if the patient is dehydrated or renal function worsens.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Other interactions of Gentamicin
- Cidofovir + Gentamicin Contraindicated
- Adefovir + Gentamicin Major
- Amikacin + Gentamicin Major
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Major
- Amphotericin b deoxycholate + Gentamicin Major
- Amphotericin b + Gentamicin Major
Frequently asked questions
Can I take Gentamicin with Telmisartan-amlodipine?
MediHelp rates the interaction as moderate. Gentamicin and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gentamicin is nephrotoxic, and with an ARB such as telmisartan, which reduces glomerular filtration pressure, the risk of acute kidney injury and electrolyte disturbance may increase. Gentamicin can also cause renal potassium and magnesium wasting.
How serious is the interaction between Gentamicin and Telmisartan-amlodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor creatinine, potassium and magnesium and gentamicin levels during therapy. Consider temporarily holding telmisartan if the patient is dehydrated or renal function worsens.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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