Drug interactions
Ginger + Mefenamic acid
Severity: Minor
Ginger and Mefenamic acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginger may inhibit platelet aggregation and could theoretically add to the bleeding risk of an NSAID. Clinical evidence of meaningful interaction is weak.
What this interaction means in plain words
Ginger and Mefenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ginger belongs to Gastrointestinal Tract; Mefenamic acid belongs to Musculoskeletal.
Why it happens
Possible additive antiplatelet effect via thromboxane synthesis inhibition by ginger constituents.
What to do
Counsel patients using concentrated ginger supplements to report unusual bruising or bleeding. No dose change is routinely needed for dietary amounts.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mefenamic acid
- Ketorolac intranasal + Mefenamic acid Contraindicated
- Ketorolac + Mefenamic acid Contraindicated
- Aceclofenac + Mefenamic acid Major
- Acemetacin + Mefenamic acid Major
- Acetylsalicylic acid + Mefenamic acid Major
- Alteplase + Mefenamic acid Major
Other interactions of Ginger
- Aceclofenac + Ginger Moderate
- Acemetacin + Ginger Moderate
- Aescin + Ginger Moderate
- Aspirin / citric acid / sodium bicarbonate + Ginger Moderate
- Aspirin rectal + Ginger Moderate
- Aspirin + Ginger Moderate
Frequently asked questions
Can I take Ginger with Mefenamic acid?
MediHelp rates the interaction as minor. Ginger and Mefenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ginger may inhibit platelet aggregation and could theoretically add to the bleeding risk of an NSAID. Clinical evidence of meaningful interaction is weak.
How serious is the interaction between Ginger and Mefenamic acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients using concentrated ginger supplements to report unusual bruising or bleeding. No dose change is routinely needed for dietary amounts.
What other medicines interact with Mefenamic acid?
MediHelp also lists interactions of Mefenamic acid with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Mefenamic acid page.
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