Drug interactions
Ginkgo biloba + Nabumetone
Severity: Moderate
Ginkgo biloba and Nabumetone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo inhibits platelet-activating factor and there are case reports of bleeding with ginkgo, so it may add to the bleeding risk of NSAIDs. Controlled studies have not consistently confirmed a significant effect.
What this interaction means in plain words
Ginkgo biloba and Nabumetone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive antiplatelet effect through platelet-activating factor antagonism and NSAID cyclooxygenase inhibition.
What to do
Advise avoiding ginkgo while taking nabumetone, or monitor for bruising, melena and other bleeding. Discontinue ginkgo before surgery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabumetone
- Ketorolac intranasal + Nabumetone Contraindicated
- Ketorolac + Nabumetone Contraindicated
- Aceclofenac + Nabumetone Major
- Acemetacin + Nabumetone Major
- Acetylsalicylic acid + Nabumetone Major
- Alteplase + Nabumetone Major
Frequently asked questions
Can I take Ginkgo biloba with Nabumetone?
MediHelp rates the interaction as moderate. Ginkgo biloba and Nabumetone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo inhibits platelet-activating factor and there are case reports of bleeding with ginkgo, so it may add to the bleeding risk of NSAIDs. Controlled studies have not consistently confirmed a significant effect.
How serious is the interaction between Ginkgo biloba and Nabumetone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding ginkgo while taking nabumetone, or monitor for bruising, melena and other bleeding. Discontinue ginkgo before surgery.
What other medicines interact with Nabumetone?
MediHelp also lists interactions of Nabumetone with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Nabumetone page.
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