Drug interactions
Ginkgo biloba + Piroxicam
Severity: Moderate
Ginkgo biloba and Piroxicam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo has antiplatelet activity via platelet-activating factor antagonism, and case reports describe bleeding with antithrombotic drugs. Combined with piroxicam, bleeding risk may be increased.
What this interaction means in plain words
Ginkgo biloba and Piroxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Ginkgolide inhibition of platelet-activating factor adds to NSAID cyclooxygenase-mediated platelet inhibition.
What to do
Advise avoiding ginkgo supplements while on piroxicam, or monitor for bleeding signs if continued.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Ginkgo biloba and Piroxicam, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Piroxicam
- Ketorolac intranasal + Piroxicam Contraindicated
- Ketorolac + Piroxicam Contraindicated
- Aceclofenac + Piroxicam Major
- Acemetacin + Piroxicam Major
- Acetylsalicylic acid + Piroxicam Major
- Alteplase + Piroxicam Major
Frequently asked questions
Can I take Ginkgo biloba with Piroxicam?
MediHelp rates the interaction as moderate. Ginkgo biloba and Piroxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo has antiplatelet activity via platelet-activating factor antagonism, and case reports describe bleeding with antithrombotic drugs. Combined with piroxicam, bleeding risk may be increased.
How serious is the interaction between Ginkgo biloba and Piroxicam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding ginkgo supplements while on piroxicam, or monitor for bleeding signs if continued.
What other medicines interact with Piroxicam?
MediHelp also lists interactions of Piroxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Piroxicam page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
