Drug interactions
Ginkgo biloba + Vitamin k1
Severity: Minor
Ginkgo biloba and Vitamin k1: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo inhibits platelet-activating factor and has been linked to bleeding reports, so it may add to bleeding risk when hemostasis is being restored with phytonadione. Evidence is mixed and the effect is probably small.
What this interaction means in plain words
Ginkgo biloba and Vitamin k1 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Ginkgolides antagonize platelet-activating factor, giving an antiplatelet effect that opposes phytonadione's benefit.
What to do
Advise avoiding ginkgo in patients with active bleeding or coagulopathy; monitor for bleeding if continued.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vitamin k1
- Vitamin k1 + Warfarin Major
- Cholestyramine + Vitamin k1 Moderate
- Colestipol + Vitamin k1 Moderate
- Ketorolac intranasal + Vitamin k1 Moderate
- Mineral oil + Vitamin k1 Moderate
- Orlistat + Vitamin k1 Moderate
Frequently asked questions
Can I take Ginkgo biloba with Vitamin k1?
MediHelp rates the interaction as minor. Ginkgo biloba and Vitamin k1 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ginkgo inhibits platelet-activating factor and has been linked to bleeding reports, so it may add to bleeding risk when hemostasis is being restored with phytonadione. Evidence is mixed and the effect is probably small.
How serious is the interaction between Ginkgo biloba and Vitamin k1?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding ginkgo in patients with active bleeding or coagulopathy; monitor for bleeding if continued.
What other medicines interact with Vitamin k1?
MediHelp also lists interactions of Vitamin k1 with, for example, Warfarin, Cholestyramine, Colestipol. The full list is on the Vitamin k1 page.
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