Drug interactions
Ginseng + Piroxicam
Severity: Moderate
Ginseng and Piroxicam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginseng may have antiplatelet activity, and piroxicam inhibits platelet function and carries a high risk of gastrointestinal ulceration. Combined use may increase bleeding risk, though clinical evidence is limited.
What this interaction means in plain words
Ginseng and Piroxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ginseng belongs to Gastrointestinal Tract; Piroxicam belongs to Musculoskeletal.
Why it happens
Additive antiplatelet effects, with NSAID-related gastrointestinal mucosal injury.
What to do
Advise patients to report black stools, unusual bruising or bleeding. Use the lowest effective piroxicam dose and stop ginseng if bleeding signs occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ginseng
- Acemetacin + Ginseng Moderate
- Alteplase + Ginseng Moderate
- Argatroban + Ginseng Moderate
- Aspirin / citric acid / sodium bicarbonate + Ginseng Moderate
- Aspirin rectal + Ginseng Moderate
- Aspirin + Ginseng Moderate
Other interactions of Piroxicam
- Ketorolac intranasal + Piroxicam Contraindicated
- Ketorolac + Piroxicam Contraindicated
- Aceclofenac + Piroxicam Major
- Acemetacin + Piroxicam Major
- Acetylsalicylic acid + Piroxicam Major
- Alteplase + Piroxicam Major
Frequently asked questions
Can I take Ginseng with Piroxicam?
MediHelp rates the interaction as moderate. Ginseng and Piroxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginseng may have antiplatelet activity, and piroxicam inhibits platelet function and carries a high risk of gastrointestinal ulceration. Combined use may increase bleeding risk, though clinical evidence is limited.
How serious is the interaction between Ginseng and Piroxicam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report black stools, unusual bruising or bleeding. Use the lowest effective piroxicam dose and stop ginseng if bleeding signs occur.
What other medicines interact with Ginseng?
MediHelp also lists interactions of Ginseng with, for example, Acemetacin, Alteplase, Argatroban. The full list is on the Ginseng page.
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