Drug interactions
Givinostat + Levetiracetam
Severity: Minor
Givinostat and Levetiracetam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Givinostat can prolong the QTc interval. Levetiracetam has only rare reports of QT effects, so any additive effect is poorly established.
What this interaction means in plain words
Givinostat and Levetiracetam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Givinostat belongs to Miscellaneous; Levetiracetam belongs to Central Nervous System.
Why it happens
Levetiracetam is not an established QT-prolonging drug, so a pharmacodynamic interaction is unproven.
What to do
Follow givinostat labeling for ECG monitoring and electrolyte correction. No levetiracetam-specific change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levetiracetam
Other interactions of Givinostat
- Abiraterone + Givinostat Major
- Amiodarone + Givinostat Major
- Amisulpride + Givinostat Major
- Amitriptyline + Givinostat Major
- Anagrelide + Givinostat Major
- Asenapine + Givinostat Major
Frequently asked questions
Can I take Givinostat with Levetiracetam?
MediHelp rates the interaction as minor. Givinostat and Levetiracetam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Givinostat can prolong the QTc interval. Levetiracetam has only rare reports of QT effects, so any additive effect is poorly established.
How serious is the interaction between Givinostat and Levetiracetam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Follow givinostat labeling for ECG monitoring and electrolyte correction. No levetiracetam-specific change is needed.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.
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