Drug interactions
Glycopyrronium + Promazine
Severity: Minor
Glycopyrronium and Promazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Promazine, a phenothiazine, has anticholinergic activity that adds to that of glycopyrronium. This may increase dry mouth, constipation, urinary retention, blurred vision and tachycardia.
What this interaction means in plain words
Glycopyrronium and Promazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive anticholinergic (antimuscarinic) effects.
What to do
Monitor for anticholinergic adverse effects, especially in older patients, and reduce doses if they become troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glycopyrronium
- Clozapine + Glycopyrronium Major
- Abobotulinumtoxina + Glycopyrronium Moderate
- Aclidinium + Glycopyrronium Moderate
- Amantadine + Glycopyrronium Moderate
- Amitriptyline + Glycopyrronium Moderate
- Amoxapine + Glycopyrronium Moderate
Frequently asked questions
Can I take Glycopyrronium with Promazine?
MediHelp rates the interaction as minor. Glycopyrronium and Promazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Promazine, a phenothiazine, has anticholinergic activity that adds to that of glycopyrronium. This may increase dry mouth, constipation, urinary retention, blurred vision and tachycardia.
How serious is the interaction between Glycopyrronium and Promazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects, especially in older patients, and reduce doses if they become troublesome.
What other medicines interact with Glycopyrronium?
MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Glycopyrronium page.
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