Drug interactions
Gold sodium thiomalate + Selinexor
Severity: Moderate
Gold sodium thiomalate and Selinexor: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can cause hematologic toxicity, and selinexor commonly causes thrombocytopenia and neutropenia, while gold can cause blood dyscrasias. Selinexor also causes dizziness and confusion, but this is not a gold interaction.
What this interaction means in plain words
Gold sodium thiomalate and Selinexor can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive myelosuppressive toxicity; no pharmacokinetic mechanism established.
What to do
Monitor complete blood counts frequently, including platelets, and stop gold if cytopenias develop.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Selinexor
- Aldesleukin + Selinexor Moderate
- Alprazolam + Selinexor Moderate
- Amitriptyline + Selinexor Moderate
- Amobarbital + Selinexor Moderate
- Aripiprazole + Selinexor Moderate
- Asenapine + Selinexor Moderate
Frequently asked questions
Can I take Gold sodium thiomalate with Selinexor?
MediHelp rates the interaction as moderate. Gold sodium thiomalate and Selinexor can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can cause hematologic toxicity, and selinexor commonly causes thrombocytopenia and neutropenia, while gold can cause blood dyscrasias. Selinexor also causes dizziness and confusion, but this is not a gold interaction.
How serious is the interaction between Gold sodium thiomalate and Selinexor?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts frequently, including platelets, and stop gold if cytopenias develop.
What other medicines interact with Selinexor?
MediHelp also lists interactions of Selinexor with, for example, Aldesleukin, Alprazolam, Amitriptyline. The full list is on the Selinexor page.
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