Drug interactions
Gotu kola + Hydroxyzine
Severity: Minor
Gotu kola and Hydroxyzine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gotu kola has traditional sedative properties and may add to the drowsiness caused by hydroxyzine. The clinical evidence is limited.
What this interaction means in plain words
Gotu kola and Hydroxyzine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depression; the mechanism is not well established.
What to do
Advise patients to watch for increased drowsiness and avoid driving if affected. Consider stopping the herbal product if sedation becomes troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydroxyzine
- Droperidol + Hydroxyzine Contraindicated
- Hydroxyzine + Pimozide Contraindicated
- Hydroxyzine + Thioridazine Contraindicated
- Hydroxyzine + Vandetanib Contraindicated
- Alfentanil + Hydroxyzine Major
- Amiodarone + Hydroxyzine Major
Frequently asked questions
Can I take Gotu kola with Hydroxyzine?
MediHelp rates the interaction as minor. Gotu kola and Hydroxyzine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Gotu kola has traditional sedative properties and may add to the drowsiness caused by hydroxyzine. The clinical evidence is limited.
How serious is the interaction between Gotu kola and Hydroxyzine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for increased drowsiness and avoid driving if affected. Consider stopping the herbal product if sedation becomes troublesome.
What other medicines interact with Hydroxyzine?
MediHelp also lists interactions of Hydroxyzine with, for example, Droperidol, Pimozide, Thioridazine. The full list is on the Hydroxyzine page.
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