Drug interactions
Griseofulvin + Nimodipine
Severity: Moderate
Griseofulvin and Nimodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin may lower nimodipine concentrations, potentially reducing its protective effect after subarachnoid hemorrhage.
What this interaction means in plain words
Griseofulvin and Nimodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Griseofulvin belongs to Anti Fungals; Nimodipine belongs to Cardiovascular.
Why it happens
CYP3A4 induction by griseofulvin increases nimodipine metabolism.
What to do
Monitor blood pressure and neurological status, and consider delaying griseofulvin if possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Griseofulvin
Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Frequently asked questions
Can I take Griseofulvin with Nimodipine?
MediHelp rates the interaction as moderate. Griseofulvin and Nimodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Griseofulvin may lower nimodipine concentrations, potentially reducing its protective effect after subarachnoid hemorrhage.
How serious is the interaction between Griseofulvin and Nimodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and neurological status, and consider delaying griseofulvin if possible.
What other medicines interact with Griseofulvin?
MediHelp also lists interactions of Griseofulvin with, for example, Cyclosporine, Cyclosporin, Desogestrel-ethinyl estradiol. The full list is on the Griseofulvin page.
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