Drug interactions
Griseofulvin + Saxagliptin
Severity: Minor
Griseofulvin and Saxagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin is a weak inducer of CYP3A4 and could lower exposure to saxagliptin and its active metabolite. The effect is expected to be small and is unlikely to alter glycemic control meaningfully.
What this interaction means in plain words
Griseofulvin and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Griseofulvin belongs to Anti Fungals; Saxagliptin belongs to Endocrine.
Why it happens
Weak CYP3A4 induction by griseofulvin may increase saxagliptin metabolism.
What to do
No dose change is normally needed; check glycemic control if griseofulvin is started or stopped during long courses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Griseofulvin
Other interactions of Saxagliptin
- Albiglutide + Saxagliptin Moderate
- Amlodipine-benazepril + Saxagliptin Moderate
- Aripiprazole + Saxagliptin Moderate
- Asenapine + Saxagliptin Moderate
- Atazanavir + Saxagliptin Moderate
- Benazepril + Saxagliptin Moderate
Frequently asked questions
Can I take Griseofulvin with Saxagliptin?
MediHelp rates the interaction as minor. Griseofulvin and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin is a weak inducer of CYP3A4 and could lower exposure to saxagliptin and its active metabolite. The effect is expected to be small and is unlikely to alter glycemic control meaningfully.
How serious is the interaction between Griseofulvin and Saxagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is normally needed; check glycemic control if griseofulvin is started or stopped during long courses.
What other medicines interact with Griseofulvin?
MediHelp also lists interactions of Griseofulvin with, for example, Cyclosporin, Desogestrel-ethinyl estradiol, Dienogest / estradiol valerate. The full list is on the Griseofulvin page.
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