Drug interactions
Griseofulvin + Vardenafil
Severity: Minor
Griseofulvin and Vardenafil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin is a CYP3A4 inducer and may lower vardenafil concentrations. This could reduce the efficacy of vardenafil during and after griseofulvin therapy.
What this interaction means in plain words
Griseofulvin and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Griseofulvin belongs to Anti Fungals; Vardenafil belongs to Genitourinary.
Why it happens
Induction of CYP3A4 increases vardenafil metabolism.
What to do
Monitor erectile response and adjust the vardenafil dose within labeled limits if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vardenafil
- Amyl nitrite + Vardenafil Contraindicated
- Glyceryl trinitrate pr + Vardenafil Contraindicated
- Isosorbide dinitrate + Vardenafil Contraindicated
- Isosorbide mononitrate + Vardenafil Contraindicated
- Nicorandil + Vardenafil Contraindicated
- Nitroglycerin po + Vardenafil Contraindicated
Other interactions of Griseofulvin
Frequently asked questions
Can I take Griseofulvin with Vardenafil?
MediHelp rates the interaction as minor. Griseofulvin and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin is a CYP3A4 inducer and may lower vardenafil concentrations. This could reduce the efficacy of vardenafil during and after griseofulvin therapy.
How serious is the interaction between Griseofulvin and Vardenafil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor erectile response and adjust the vardenafil dose within labeled limits if needed.
What other medicines interact with Vardenafil?
MediHelp also lists interactions of Vardenafil with, for example, Amyl nitrite, Glyceryl trinitrate pr, Isosorbide dinitrate. The full list is on the Vardenafil page.
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