Drug interactions
Haemophilus influenzae type b vaccine + Oxaliplatin
Severity: Moderate
Haemophilus influenzae type b vaccine and Oxaliplatin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chemotherapy with oxaliplatin may reduce the antibody response to Hib vaccine. Protection may be suboptimal if vaccination occurs during treatment.
What this interaction means in plain words
Haemophilus influenzae type b vaccine and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Cytotoxic immunosuppression reduces vaccine immunogenicity.
What to do
Avoid vaccinating during chemotherapy if possible. Revaccinate at least 3 months after therapy if given within 14 days before or during treatment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Haemophilus influenzae type b vaccine and Oxaliplatin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Frequently asked questions
Can I take Haemophilus influenzae type b vaccine with Oxaliplatin?
MediHelp rates the interaction as moderate. Haemophilus influenzae type b vaccine and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chemotherapy with oxaliplatin may reduce the antibody response to Hib vaccine. Protection may be suboptimal if vaccination occurs during treatment.
How serious is the interaction between Haemophilus influenzae type b vaccine and Oxaliplatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vaccinating during chemotherapy if possible. Revaccinate at least 3 months after therapy if given within 14 days before or during treatment.
What other medicines interact with Oxaliplatin?
MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
