Drug interactions
Haloperidol + Indacaterol inhaled
Severity: Moderate
Haloperidol and Indacaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled indacaterol, a long-acting beta-agonist, can cause tachycardia, hypokalemia and QT prolongation at high exposure. With haloperidol the risk of ventricular arrhythmia may be increased, particularly in those with cardiac disease.
What this interaction means in plain words
Haloperidol and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia and sympathetic stimulation.
What to do
Use the recommended indacaterol dose only and consider an ECG at baseline for at-risk patients. Monitor potassium and correct deficiencies.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Frequently asked questions
Can I take Haloperidol with Indacaterol inhaled?
MediHelp rates the interaction as moderate. Haloperidol and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Inhaled indacaterol, a long-acting beta-agonist, can cause tachycardia, hypokalemia and QT prolongation at high exposure. With haloperidol the risk of ventricular arrhythmia may be increased, particularly in those with cardiac disease.
How serious is the interaction between Haloperidol and Indacaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the recommended indacaterol dose only and consider an ECG at baseline for at-risk patients. Monitor potassium and correct deficiencies.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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