Drug interactions
Haloperidol + Levosalbutamol
Severity: Moderate
Haloperidol and Levosalbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Haloperidol can prolong the QT interval, and beta-2 agonists at high doses may add to this effect and lower potassium. The combined risk of ventricular arrhythmia is mostly relevant in patients with other risk factors.
What this interaction means in plain words
Haloperidol and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Haloperidol belongs to Central Nervous System; Levosalbutamol belongs to Respiratory.
Why it happens
Additive effects on cardiac repolarization, with beta-agonist hypokalemia increasing susceptibility.
What to do
Check potassium and magnesium, and obtain an ECG in patients using high doses of levosalbutamol or having other QT risk factors. Correct electrolyte abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levosalbutamol
Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Frequently asked questions
Can I take Haloperidol with Levosalbutamol?
MediHelp rates the interaction as moderate. Haloperidol and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Haloperidol can prolong the QT interval, and beta-2 agonists at high doses may add to this effect and lower potassium. The combined risk of ventricular arrhythmia is mostly relevant in patients with other risk factors.
How serious is the interaction between Haloperidol and Levosalbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium, and obtain an ECG in patients using high doses of levosalbutamol or having other QT risk factors. Correct electrolyte abnormalities.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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