Drug interactions
Haloperidol + Lormetazepam
Severity: Moderate
Haloperidol and Lormetazepam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Concurrent use of a benzodiazepine hypnotic and haloperidol increases drowsiness, impaired coordination and hypotension. Falls and next-day impairment are the main concerns.
What this interaction means in plain words
Haloperidol and Lormetazepam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive central nervous system depression.
What to do
Use the lowest effective doses and monitor for oversedation and falls, especially in older adults. Counsel patients to avoid alcohol and driving.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Frequently asked questions
Can I take Haloperidol with Lormetazepam?
MediHelp rates the interaction as moderate. Haloperidol and Lormetazepam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Concurrent use of a benzodiazepine hypnotic and haloperidol increases drowsiness, impaired coordination and hypotension. Falls and next-day impairment are the main concerns.
How serious is the interaction between Haloperidol and Lormetazepam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and monitor for oversedation and falls, especially in older adults. Counsel patients to avoid alcohol and driving.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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