Drug interactions
Haloperidol + Quazepam
Severity: Moderate
Haloperidol and Quazepam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quazepam is a benzodiazepine hypnotic and combined with haloperidol increases sedation, psychomotor impairment and risk of respiratory depression. Falls and next-day impairment are a particular concern in older adults.
What this interaction means in plain words
Haloperidol and Quazepam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression.
What to do
Use the lowest effective doses and monitor sedation and respiratory status. Advise against driving and alcohol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Frequently asked questions
Can I take Haloperidol with Quazepam?
MediHelp rates the interaction as moderate. Haloperidol and Quazepam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quazepam is a benzodiazepine hypnotic and combined with haloperidol increases sedation, psychomotor impairment and risk of respiratory depression. Falls and next-day impairment are a particular concern in older adults.
How serious is the interaction between Haloperidol and Quazepam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and monitor sedation and respiratory status. Advise against driving and alcohol.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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