Drug interactions
Henbane + Indacaterol-glycopyrronium
Severity: Moderate
Henbane and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Henbane contains the antimuscarinic alkaloids hyoscyamine and scopolamine. With inhaled glycopyrronium, additive anticholinergic effects such as dry mouth, urinary retention, constipation, tachycardia and confusion may occur.
What this interaction means in plain words
Henbane and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antimuscarinic effects.
What to do
Avoid concurrent use where possible and monitor for anticholinergic toxicity in older patients or those with glaucoma or urinary retention.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Frequently asked questions
Can I take Henbane with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Henbane and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Henbane contains the antimuscarinic alkaloids hyoscyamine and scopolamine. With inhaled glycopyrronium, additive anticholinergic effects such as dry mouth, urinary retention, constipation, tachycardia and confusion may occur.
How serious is the interaction between Henbane and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where possible and monitor for anticholinergic toxicity in older patients or those with glaucoma or urinary retention.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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