Drug interactions
Henbane + Ipratropium
Severity: Moderate
Henbane and Ipratropium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Henbane contains hyoscyamine and scopolamine, which are antimuscarinic alkaloids, so combining it with ipratropium can add to anticholinergic effects. Effects range from dry mouth and constipation to confusion, tachycardia and urinary retention.
What this interaction means in plain words
Henbane and Ipratropium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive muscarinic receptor blockade from plant-derived tropane alkaloids.
What to do
Avoid henbane use with ipratropium, as its alkaloid content is variable and toxicity is possible. Monitor for anticholinergic toxicity if exposure has occurred.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium
- Aclidinium + Ipratropium Moderate
- Benztropine + Ipratropium Moderate
- Bethanechol + Ipratropium Moderate
- Cevimeline + Ipratropium Moderate
- Chlorpromazine + Ipratropium Moderate
- Clomipramine + Ipratropium Moderate
Frequently asked questions
Can I take Henbane with Ipratropium?
MediHelp rates the interaction as moderate. Henbane and Ipratropium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Henbane contains hyoscyamine and scopolamine, which are antimuscarinic alkaloids, so combining it with ipratropium can add to anticholinergic effects. Effects range from dry mouth and constipation to confusion, tachycardia and urinary retention.
How serious is the interaction between Henbane and Ipratropium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid henbane use with ipratropium, as its alkaloid content is variable and toxicity is possible. Monitor for anticholinergic toxicity if exposure has occurred.
What other medicines interact with Ipratropium?
MediHelp also lists interactions of Ipratropium with, for example, Aclidinium, Benztropine, Bethanechol. The full list is on the Ipratropium page.
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