Drug interactions
Henbane + Succinylcholine
Severity: Minor
Henbane and Succinylcholine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Henbane contains tropane anticholinergic alkaloids such as hyoscyamine and scopolamine. They oppose the muscarinic effects of succinylcholine, such as bradycardia, and have little effect on neuromuscular blockade. The anticholinergic burden may add to tachycardia and confusion in the perioperative setting.
What this interaction means in plain words
Henbane and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Muscarinic receptor blockade by tropane alkaloids counteracts the muscarinic effects of succinylcholine.
What to do
Ask about herbal use before surgery and stop henbane preparations beforehand. Monitor heart rate and watch for anticholinergic toxicity.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Succinylcholine
Frequently asked questions
Can I take Henbane with Succinylcholine?
MediHelp rates the interaction as minor. Henbane and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Henbane contains tropane anticholinergic alkaloids such as hyoscyamine and scopolamine. They oppose the muscarinic effects of succinylcholine, such as bradycardia, and have little effect on neuromuscular blockade. The anticholinergic burden may add to tachycardia and confusion in the perioperative setting.
How serious is the interaction between Henbane and Succinylcholine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal use before surgery and stop henbane preparations beforehand. Monitor heart rate and watch for anticholinergic toxicity.
What other medicines interact with Succinylcholine?
MediHelp also lists interactions of Succinylcholine with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Succinylcholine page.
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