Drug interactions
Hydralazine + Nadolol
Severity: Minor
Hydralazine and Nadolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The combination lowers blood pressure more than either drug alone, which is often therapeutically intended. Nadolol also limits hydralazine reflex tachycardia, but hypotension or bradycardia can occur.
What this interaction means in plain words
Hydralazine and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydralazine belongs to Cardiovascular; Nadolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive effect from vasodilation and beta blockade.
What to do
Monitor blood pressure and heart rate during initiation and dose changes. Adjust doses if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydralazine
- Amifostine + Hydralazine Major
- Aceclofenac + Hydralazine Moderate
- Acemetacin + Hydralazine Moderate
- Aldesleukin + Hydralazine Moderate
- Avanafil + Hydralazine Moderate
- Benzphetamine + Hydralazine Moderate
Other interactions of Nadolol
- Acebutolol + Nadolol Major
- Adrenaline-articaine + Nadolol Major
- Albuterol + Nadolol Major
- Amifostine + Nadolol Major
- Amiodarone + Nadolol Major
- Arformoterol + Nadolol Major
Frequently asked questions
Can I take Hydralazine with Nadolol?
MediHelp rates the interaction as minor. Hydralazine and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The combination lowers blood pressure more than either drug alone, which is often therapeutically intended. Nadolol also limits hydralazine reflex tachycardia, but hypotension or bradycardia can occur.
How serious is the interaction between Hydralazine and Nadolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during initiation and dose changes. Adjust doses if symptomatic hypotension occurs.
What other medicines interact with Hydralazine?
MediHelp also lists interactions of Hydralazine with, for example, Amifostine, Aceclofenac, Acemetacin. The full list is on the Hydralazine page.
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