Drug interactions
Hydrochlorothiazide-lisinopril + Maitake
Severity: Minor
Hydrochlorothiazide-lisinopril and Maitake: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maitake mushroom may lower blood pressure and blood glucose, so it might add to the antihypertensive effect of this combination. The suggested additive potassium-lowering effect is theoretical. Clinical data are scarce.
What this interaction means in plain words
Hydrochlorothiazide-lisinopril and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive blood pressure lowering; the mechanism is not well established.
What to do
Monitor blood pressure and electrolytes if maitake supplements are used regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-lisinopril
- Dofetilide + Hydrochlorothiazide-lisinopril Contraindicated
- Hydrochlorothiazide-lisinopril + Sacubitril / valsartan Contraindicated
- Amifostine + Hydrochlorothiazide-lisinopril Major
- Amiloride + Hydrochlorothiazide-lisinopril Major
- Benazepril + Hydrochlorothiazide-lisinopril Major
- Bendroflumethiazide + Hydrochlorothiazide-lisinopril Major
Frequently asked questions
Can I take Hydrochlorothiazide-lisinopril with Maitake?
MediHelp rates the interaction as minor. Hydrochlorothiazide-lisinopril and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom may lower blood pressure and blood glucose, so it might add to the antihypertensive effect of this combination. The suggested additive potassium-lowering effect is theoretical. Clinical data are scarce.
How serious is the interaction between Hydrochlorothiazide-lisinopril and Maitake?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and electrolytes if maitake supplements are used regularly.
What other medicines interact with Hydrochlorothiazide-lisinopril?
MediHelp also lists interactions of Hydrochlorothiazide-lisinopril with, for example, Dofetilide, Sacubitril / valsartan, Amifostine. The full list is on the Hydrochlorothiazide-lisinopril page.
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