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Drug interactions

Hydrochlorothiazide-lisinopril + Methyl aminolevulinate

Severity: Minor

Hydrochlorothiazide-lisinopril and Methyl aminolevulinate: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Hydrochlorothiazide can cause photosensitivity, and methyl aminolevulinate is used topically for photodynamic therapy. Systemic photosensitizers may theoretically intensify the skin reaction to light during treatment, though topical absorption is small.

What this interaction means in plain words

Hydrochlorothiazide-lisinopril and Methyl aminolevulinate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive photosensitization; systemic exposure to the topical agent is low.

What to do

Advise sun protection and tell patients to report severe burning or blistering after illumination. No dose change is normally needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Hydrochlorothiazide-lisinopril with Methyl aminolevulinate?

MediHelp rates the interaction as minor. Hydrochlorothiazide-lisinopril and Methyl aminolevulinate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydrochlorothiazide can cause photosensitivity, and methyl aminolevulinate is used topically for photodynamic therapy. Systemic photosensitizers may theoretically intensify the skin reaction to light during treatment, though topical absorption is small.

How serious is the interaction between Hydrochlorothiazide-lisinopril and Methyl aminolevulinate?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise sun protection and tell patients to report severe burning or blistering after illumination. No dose change is normally needed.

What other medicines interact with Hydrochlorothiazide-lisinopril?

MediHelp also lists interactions of Hydrochlorothiazide-lisinopril with, for example, Dofetilide, Sacubitril / valsartan, Amifostine. The full list is on the Hydrochlorothiazide-lisinopril page.

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