Drug interactions
Hydrochlorothiazide-lisinopril + Mometasone inhaled
Severity: Minor
Hydrochlorothiazide-lisinopril and Mometasone inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids can promote potassium loss, which may add to thiazide-induced hypokalemia. With inhaled mometasone, systemic exposure is low, so the effect is usually small and relevant mainly at high doses or in patients with other risk factors.
What this interaction means in plain words
Hydrochlorothiazide-lisinopril and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mineralocorticoid activity of corticosteroids increases renal potassium excretion, adding to thiazide effects.
What to do
No routine action is needed at standard doses; check potassium if high doses are used or other hypokalemic factors exist.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-lisinopril
- Dofetilide + Hydrochlorothiazide-lisinopril Contraindicated
- Hydrochlorothiazide-lisinopril + Sacubitril / valsartan Contraindicated
- Amifostine + Hydrochlorothiazide-lisinopril Major
- Amiloride + Hydrochlorothiazide-lisinopril Major
- Benazepril + Hydrochlorothiazide-lisinopril Major
- Bendroflumethiazide + Hydrochlorothiazide-lisinopril Major
Frequently asked questions
Can I take Hydrochlorothiazide-lisinopril with Mometasone inhaled?
MediHelp rates the interaction as minor. Hydrochlorothiazide-lisinopril and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids can promote potassium loss, which may add to thiazide-induced hypokalemia. With inhaled mometasone, systemic exposure is low, so the effect is usually small and relevant mainly at high doses or in patients with other risk factors.
How serious is the interaction between Hydrochlorothiazide-lisinopril and Mometasone inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed at standard doses; check potassium if high doses are used or other hypokalemic factors exist.
What other medicines interact with Hydrochlorothiazide-lisinopril?
MediHelp also lists interactions of Hydrochlorothiazide-lisinopril with, for example, Dofetilide, Sacubitril / valsartan, Amifostine. The full list is on the Hydrochlorothiazide-lisinopril page.
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