Drug interactions
Hydrochlorothiazide-telmisartan + Methoxsalen
Severity: Moderate
Hydrochlorothiazide-telmisartan and Methoxsalen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide is a known photosensitizer and methoxsalen is a potent photosensitizing agent used with UVA light. Together they may increase the risk of severe phototoxic reactions such as burns.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Methoxsalen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hydrochlorothiazide-telmisartan belongs to Cardiovascular; Methoxsalen belongs to Anti Fungals.
Why it happens
Additive photosensitizing effects of both drugs on the skin.
What to do
Counsel on strict sun protection and protective eyewear, and review the phototherapy dose. Consider an alternative antihypertensive if photosensitivity occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Other interactions of Methoxsalen
- Fezolinetant + Methoxsalen Contraindicated
- Demeclocycline + Methoxsalen Major
- Fedratinib + Methoxsalen Major
- Methoxsalen + Pirfenidone Major
- Methoxsalen + Tasimelteon Major
- Adapalene + Methoxsalen Moderate
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Methoxsalen?
MediHelp rates the interaction as moderate. Hydrochlorothiazide-telmisartan and Methoxsalen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydrochlorothiazide is a known photosensitizer and methoxsalen is a potent photosensitizing agent used with UVA light. Together they may increase the risk of severe phototoxic reactions such as burns.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Methoxsalen?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on strict sun protection and protective eyewear, and review the phototherapy dose. Consider an alternative antihypertensive if photosensitivity occurs.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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