Drug interactions
Hydrochlorothiazide-telmisartan + Nadolol
Severity: Minor
Hydrochlorothiazide-telmisartan and Nadolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nadolol and telmisartan/hydrochlorothiazide are often combined and have additive blood pressure lowering. Hypotension and bradycardia may occur, and nadolol is renally cleared so volume depletion or reduced renal function may increase its effects.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydrochlorothiazide-telmisartan belongs to Cardiovascular; Nadolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive pharmacodynamic effects through beta-blockade, angiotensin receptor blockade and diuresis.
What to do
Monitor blood pressure and heart rate, and renal function in susceptible patients. Adjust doses if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Other interactions of Nadolol
- Acebutolol + Nadolol Major
- Adrenaline-articaine + Nadolol Major
- Albuterol + Nadolol Major
- Amifostine + Nadolol Major
- Amiodarone + Nadolol Major
- Arformoterol + Nadolol Major
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Nadolol?
MediHelp rates the interaction as minor. Hydrochlorothiazide-telmisartan and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nadolol and telmisartan/hydrochlorothiazide are often combined and have additive blood pressure lowering. Hypotension and bradycardia may occur, and nadolol is renally cleared so volume depletion or reduced renal function may increase its effects.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Nadolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, and renal function in susceptible patients. Adjust doses if symptomatic hypotension occurs.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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