Drug interactions
Hydroxyzine + Levosalbutamol
Severity: Minor
Hydroxyzine and Levosalbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydroxyzine can prolong the QT interval, and high-dose beta-2 agonists may add to this effect, especially with hypokalemia. The additional risk with usual levosalbutamol doses is likely small.
What this interaction means in plain words
Hydroxyzine and Levosalbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydroxyzine belongs to Respiratory; Levosalbutamol belongs to Respiratory.
Why it happens
Possible additive effects on cardiac repolarization, with beta-agonist hypokalemia increasing susceptibility.
What to do
No routine action is needed at usual doses. Check potassium and consider ECG monitoring if high-dose levosalbutamol is used or other QT risk factors are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Hydroxyzine and Levosalbutamol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Levosalbutamol
Other interactions of Hydroxyzine
- Droperidol + Hydroxyzine Contraindicated
- Hydroxyzine + Pimozide Contraindicated
- Hydroxyzine + Thioridazine Contraindicated
- Hydroxyzine + Vandetanib Contraindicated
- Alfentanil + Hydroxyzine Major
- Amiodarone + Hydroxyzine Major
Frequently asked questions
Can I take Hydroxyzine with Levosalbutamol?
MediHelp rates the interaction as minor. Hydroxyzine and Levosalbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydroxyzine can prolong the QT interval, and high-dose beta-2 agonists may add to this effect, especially with hypokalemia. The additional risk with usual levosalbutamol doses is likely small.
How serious is the interaction between Hydroxyzine and Levosalbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed at usual doses. Check potassium and consider ECG monitoring if high-dose levosalbutamol is used or other QT risk factors are present.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
