Drug interactions
Hydroxyzine + Metaproterenol
Severity: Minor
Hydroxyzine and Metaproterenol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydroxyzine is sedating while metaproterenol is a beta-agonist that can cause stimulation, tremor and tachycardia. The net effect on alertness is unpredictable and no meaningful clinical interaction is established.
What this interaction means in plain words
Hydroxyzine and Metaproterenol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing central effects (antihistaminic sedation versus sympathomimetic stimulation); no established pharmacokinetic mechanism.
What to do
No routine action is needed; counsel the patient that alertness may vary and monitor heart rate if palpitations occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydroxyzine
- Droperidol + Hydroxyzine Contraindicated
- Hydroxyzine + Pimozide Contraindicated
- Hydroxyzine + Thioridazine Contraindicated
- Hydroxyzine + Vandetanib Contraindicated
- Alfentanil + Hydroxyzine Major
- Amiodarone + Hydroxyzine Major
Frequently asked questions
Can I take Hydroxyzine with Metaproterenol?
MediHelp rates the interaction as minor. Hydroxyzine and Metaproterenol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydroxyzine is sedating while metaproterenol is a beta-agonist that can cause stimulation, tremor and tachycardia. The net effect on alertness is unpredictable and no meaningful clinical interaction is established.
How serious is the interaction between Hydroxyzine and Metaproterenol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; counsel the patient that alertness may vary and monitor heart rate if palpitations occur.
What other medicines interact with Hydroxyzine?
MediHelp also lists interactions of Hydroxyzine with, for example, Droperidol, Pimozide, Thioridazine. The full list is on the Hydroxyzine page.
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