Drug interactions
Hydroxyzine + Motherwort
Severity: Minor
Hydroxyzine and Motherwort: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Motherwort is a herbal product traditionally used for its mild sedative properties. Taken with hydroxyzine it may add to drowsiness and impair psychomotor performance.
What this interaction means in plain words
Hydroxyzine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive CNS depression through H1-antagonism and the herb's presumed sedative activity; evidence is largely theoretical.
What to do
Advise patients to watch for excess drowsiness and avoid driving until response is known; stop the herbal product if sedation is excessive.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydroxyzine
- Droperidol + Hydroxyzine Contraindicated
- Hydroxyzine + Pimozide Contraindicated
- Hydroxyzine + Thioridazine Contraindicated
- Hydroxyzine + Vandetanib Contraindicated
- Alfentanil + Hydroxyzine Major
- Amiodarone + Hydroxyzine Major
Frequently asked questions
Can I take Hydroxyzine with Motherwort?
MediHelp rates the interaction as minor. Hydroxyzine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort is a herbal product traditionally used for its mild sedative properties. Taken with hydroxyzine it may add to drowsiness and impair psychomotor performance.
How serious is the interaction between Hydroxyzine and Motherwort?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for excess drowsiness and avoid driving until response is known; stop the herbal product if sedation is excessive.
What other medicines interact with Hydroxyzine?
MediHelp also lists interactions of Hydroxyzine with, for example, Droperidol, Pimozide, Thioridazine. The full list is on the Hydroxyzine page.
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