Drug interactions
Hydroxyzine + Terbutaline
Severity: Minor
Hydroxyzine and Terbutaline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydroxyzine has QT-prolonging potential, and terbutaline can cause tachycardia and hypokalemia, so arrhythmic risk may increase modestly. Hydroxyzine sedation is not reliably offset by terbutaline.
What this interaction means in plain words
Hydroxyzine and Terbutaline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydroxyzine belongs to Respiratory; Terbutaline belongs to Respiratory.
Why it happens
Possible additive QT-prolongation risk from hydroxyzine and beta-agonist-induced hypokalemia.
What to do
Monitor ECG and potassium in patients with QT risk factors or on high doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Terbutaline
Other interactions of Hydroxyzine
- Droperidol + Hydroxyzine Contraindicated
- Hydroxyzine + Pimozide Contraindicated
- Hydroxyzine + Thioridazine Contraindicated
- Hydroxyzine + Vandetanib Contraindicated
- Alfentanil + Hydroxyzine Major
- Amiodarone + Hydroxyzine Major
Frequently asked questions
Can I take Hydroxyzine with Terbutaline?
MediHelp rates the interaction as minor. Hydroxyzine and Terbutaline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydroxyzine has QT-prolonging potential, and terbutaline can cause tachycardia and hypokalemia, so arrhythmic risk may increase modestly. Hydroxyzine sedation is not reliably offset by terbutaline.
How serious is the interaction between Hydroxyzine and Terbutaline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and potassium in patients with QT risk factors or on high doses.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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