Drug interactions
Hyoscyamine spray + Indacaterol-glycopyrronium
Severity: Moderate
Hyoscyamine spray and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral-mucosal hyoscyamine is absorbed systemically. Combined with inhaled glycopyrronium it may cause additive dry mouth, urinary retention, constipation, tachycardia and confusion.
What this interaction means in plain words
Hyoscyamine spray and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antimuscarinic effects.
What to do
Monitor for anticholinergic effects, especially in older adults, and avoid in narrow-angle glaucoma or urinary retention.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Hyoscyamine spray and Indacaterol-glycopyrronium, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Indacaterol-glycopyrronium
Frequently asked questions
Can I take Hyoscyamine spray with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Hyoscyamine spray and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral-mucosal hyoscyamine is absorbed systemically. Combined with inhaled glycopyrronium it may cause additive dry mouth, urinary retention, constipation, tachycardia and confusion.
How serious is the interaction between Hyoscyamine spray and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects, especially in older adults, and avoid in narrow-angle glaucoma or urinary retention.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
