Drug interactions
Ibandronate + Voclosporin
Severity: Moderate
Ibandronate and Voclosporin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voclosporin can cause dose-related nephrotoxicity, and ibandronate is renally eliminated and can rarely worsen renal function. Together they may increase renal risk, especially in patients with reduced baseline kidney function.
What this interaction means in plain words
Ibandronate and Voclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ibandronate belongs to Musculoskeletal; Voclosporin belongs to Miscellaneous.
Why it happens
Additive nephrotoxic potential, with reduced renal clearance of ibandronate if renal function falls.
What to do
Monitor serum creatinine and eGFR regularly and avoid ibandronate if renal function drops below its labeled threshold.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ibandronate
- Aluminum hydroxide + Ibandronate Moderate
- Calcium acetate + Ibandronate Moderate
- Calcium carbonate + Ibandronate Moderate
- Calcium chloride + Ibandronate Moderate
- Calcium citrate + Ibandronate Moderate
- Calcium gluconate + Ibandronate Moderate
Other interactions of Voclosporin
- Clarithromycin + Voclosporin Contraindicated
- Cyclosporin + Voclosporin Contraindicated
- Ensitrelvir + Voclosporin Contraindicated
- Itraconazole + Voclosporin Contraindicated
- Ketoconazole + Voclosporin Contraindicated
- Posaconazole + Voclosporin Contraindicated
Frequently asked questions
Can I take Ibandronate with Voclosporin?
MediHelp rates the interaction as moderate. Ibandronate and Voclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Voclosporin can cause dose-related nephrotoxicity, and ibandronate is renally eliminated and can rarely worsen renal function. Together they may increase renal risk, especially in patients with reduced baseline kidney function.
How serious is the interaction between Ibandronate and Voclosporin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and eGFR regularly and avoid ibandronate if renal function drops below its labeled threshold.
What other medicines interact with Ibandronate?
MediHelp also lists interactions of Ibandronate with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Ibandronate page.
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