Drug interactions
Ibutilide + Telavancin
Severity: Major
Ibutilide and Telavancin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ibutilide is a class III antiarrhythmic with a high, well-documented risk of torsades de pointes. Adding telavancin, which can lengthen the QT interval, could increase that risk further.
What this interaction means in plain words
Ibutilide and Telavancin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ibutilide belongs to Cardiovascular; Telavancin belongs to Anti Bacterial.
Why it happens
Additive pharmacodynamic QT prolongation, with ibutilide as the dominant contributor.
What to do
Avoid telavancin around ibutilide administration and choose another antibiotic. If unavoidable, give ibutilide with continuous ECG monitoring and with potassium and magnesium corrected.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Ibutilide
- Amiodarone + Ibutilide Contraindicated
- Amisulpride + Ibutilide Contraindicated
- Chlorpromazine + Ibutilide Contraindicated
- Clarithromycin + Ibutilide Contraindicated
- Desipramine + Ibutilide Contraindicated
- Dolasetron + Ibutilide Contraindicated
Frequently asked questions
Can I take Ibutilide with Telavancin?
MediHelp rates the interaction as major. Ibutilide and Telavancin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ibutilide is a class III antiarrhythmic with a high, well-documented risk of torsades de pointes. Adding telavancin, which can lengthen the QT interval, could increase that risk further.
How serious is the interaction between Ibutilide and Telavancin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid telavancin around ibutilide administration and choose another antibiotic. If unavoidable, give ibutilide with continuous ECG monitoring and with potassium and magnesium corrected.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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